
July 2007
New recommendations for breast MRI
By Kathleen Gafarian, M.D., St. John's Breast Center
New evidence suggests that women who are at
high risk for breast cancer may benefit from MRI. The panel convened by
the ACS says in addition to mammography, annual screening using MRI is
recommended for women who:
- have a BRCA 1 or
2 mutation
- have a
first-degree relative with a BRCA 1 or 2 mutation and are untested
- have a lifetime
risk of breast cancer of 20-25 percent or more using standard risk
assessment models*
- received
radiation treatment to the chest between ages 10 and 30, such as for
Hodgkin's disease
- carry or have a
first-degree relative who carries a genetic mutation in the TP53 or PTEN
genes (Li-Fraumeni syndrome and Cowden and Bannayan-Riley-Ruvalcaba
syndromes).
A
personal history of breast cancer alone does not warrant screening with
MRI. Breast MRI has a low specificity for cancer which leads to many more
false positive results than mammography. Experts stress how imperative it
is to carefully select those women who should be screened using this
technology. A researched risk model such as BRCAPRO, Claus model or the
Gail model should be used to determine a woman’s lifetime risk of breast
cancer.
Since
January 2006, St. John’s Breast Center in collaboration with St. John’s
MRI department has provided breast MRI for women newly diagnosed with
breast cancer to help determine the extent of the disease. Selection
criteria have been carefully monitored to assure appropriate use of the
technology.
The
Breast Center will incorporate the new screening guidelines into its
breast MRI protocols. A risk model will be utilized as part of the
selection criteria. More details will be provided as the protocols become
finalized in the fall.
Read more about St. John's Breast Center
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